Aside from a few cards which I've done with digital media, most of my mooted deck have been drawn by hand. Then the process is that they're cleaned up a bit digitally, printed out on art paper, coloured and then scanned in again. Which is a pretty roundabout system, but it works. I find that colouring digitally doesn't actually create the effect I want, and it isn't any less work. I'm enjoying the cards so far... But then I've only done a dozen and I'm sure that come card 78 I'll be sick of them.